A doctoral thesis at the College of Science at the University of Karbala discussed the preparation and study of the biological activity of some new 2-aminobenzothiazole derivatives.
The study, which was presented by student Nour Al-Huda Muhammad Abdel-Hussein from the Department of Chemistry Sciences, aimed to prepare new benzothiazole derivatives containing thiazolidinone, quinazolinone, and chalcone units and diagnose them using approved spectroscopic analysis methods.
The study concluded that most of the compounds contain DPPH radical inhibitory properties, which are particularly strong and superior to ascorbic acid. Some of the prepared compounds were more effective than gentamycin as a drug against (S. aureus) and (E. coli).
The study recommended conducting extensive investigations to ensure the minimum affected concentration and toxicity of the new prepared compounds, and studying the biological effects of these compounds on different types of bacteria, fungi, viruses, and diseases that affect animal tissues.
