A doctoral and teaching student at the College of Dentistry / University of Karbala, Shaima Fadl Mohsen, discussed her thesis titled Detection of human papillomavirus in relation to biological behavior using the proliferative marker Ki67 and the prognostic marker p53 in Schneideroma papilloma
The objective of the thesis was to describe the impact of HPV infection, as well as to examine the predictive role of proliferative and proliferative markers in relation to dysplasia across biological behaviors through the use of low- and high-risk human PCR. Human papilloma virus as well as immunohistochemical detection of vital parameters
The thesis included the selection of 35 paraffin-embedded Schneideroma papillomas from the nasal tract, where monoclonal antibodies were used for immunohistochemical staining of nasal sinus papilloma tissues to detect (Ki-67 and p53). Dako quantitative immunohistochemical analysis was performed to analyze the results, on the tissues, PCR was performed for HPV serotypes 16/18 and 6/11.
The results showed that proliferative, apoptotic, and viral expression had no significant effect in determining the biological behavior of Schneider’s papillary tumor considering dysplasia.
Faraqed Abd Al-Ridha / Media of the College
