fluoride

Although water fluoridation has been hailed as one of the greatest medical achievements of the 20th century,[10] toothpastes containing fluoride can be toxic if swallowed in large amounts.[13][14] The risk of fluoride use is so low that full-strength toothpaste (1350-1500 ppm fluoride) is recommended for all ages (although smaller amounts are used for children; a “spot” of toothpaste up to three years of age).[14] ] The primary concern of fluoride toxicity to humans is in children under 12 months of age when they ingest excessive fluoride via toothpaste. There are many fluoride-free toothpastes out there.