When a tooth is missing, it causes extra space between the teeth and in the long run, the teeth will move and the result will be lopsided teeth. Also, gums can become infected through direct contact with food or drinks. It will lead to erosion of the lateral teeth and erosion and deformation of the jaw bone.
You can see the article link below:
Missing upper incisors: a retrospective study of orthodontic space closure versus implant
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